植松智特任教授、井元清哉教授らの研究グループは、腸内細菌ゲノムと腸内ウイルスゲノムを当センターの SHIROKANE により網羅的に解析することで疾患特異的な腸内細菌の制御を可能とする新規抗菌物質の同定に成功しました。
掲載誌: Cell Host & Microbe 7 月 11 日オンライン版 DOI: 10.1016/j.chom.2020.06.005 Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts. 詳しくは東大医科研プレスリリースをご覧ください。
Large-scale data analysis of viral dark matter using SHIROKANE to identify new antimicrobial agents: Paving the way for new therapies with enzymes derived from viruses
The research group led by Professors Satoshi Uematsu, Seiya Imoto and others has used SHIROKANE to study the effects of intestinal bacteria and a novel antimicrobial agent that enables comprehensive analysis of the genomes of intestinal viruses and control of disease-specific intestinal bacteria The substance was successfully identified.
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